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FACULTY

Position: HOME > PI



Depei Wu, Ph.D.

 

199 Ren'ai Rd. Suzhou, Jiangsu 215123, P.R.China

Institute of Blood and Marrow Transplantation (IBMT), Soochow University

Phone:

Fax:

E-mail: wudepei@medmail.com.cn

 

Education:

1978-1982, B.S., Medicine, Soochow Medical College;

1985-1988, M.S., Medicine, Soochow Medical College;

1995-1998, Ph.D., Medicine, Soochow Medical College;

 

Professional Experience:

1994-2001, The First Afflicated Hospital of Soochow University, Hematology department, Associate Chief Physician, Associate Professor;

2001-present, The First Afflicated Hospital of Soochow University, Hematology department, Chief Physician, Professor;

 

Research:           

Experimental and Clinical Hematopoietic Stem Cell Transplantation (HSCT)

 

Representative Publications

*corresponding author#co-first author)

1.         Yu Wang#, Qi-Fa Liu#, Lan-Ping Xu, KaiYan Liu, Xiao-Hui Zhang, Xiao Ma, Zhi-Ping Fan, De-Pei Wu*, and Xiao-Jun Huang*, Haploidentical vs identical-sibling transplant for AML in remission: a multicenter, prospective study. Blood, 2015, 125(25): 3956-62

2.         Yue Han, Ya-qiong Tang, Jia Chen, Jian-ying Liang, Chun-mei Ye, Chang-geng Ruan, De-pei Wu*, Low-Dose Decitabine for Patients With Thrombocytopenia Following Allogeneic Hematopoietic Stem Cell Transplantation: A Pilot Therapeutic Study. JAMA Oncol, 2015 May, 1(2):249-51

3.         Yue-jun Liu#,Yan Wu#, Ying Wang, Yi-feng Cai, Bo Hu, Guang-ming Bao, Hong-ying Fang, Li-xiang Zhao, Shou-bao Ma, Qiao Cheng, Yuan Song, Yong-hao Liu, Zi-ling Zhu, Hui-rong Chang, Xiao Yu, Ai-ning Sun, Yi Zhang, Dario A. A. Vignali, De-pei Wu*, and Hai-yan Liu*, IL-35 mitigates murine acute graft-versus-host disease with retention of graft-versus-leukemia effects. Leukemia. 2015 Apr, 29(4):939-46

4.         Xiao-wen Tang, Yao-hua Song, Ai-ning Sun, Xia-ming Zhu, Chang-gen Ruan, De-pei Wu*, Successful Treatment of Relapsed Acute Myeloid Leukemia Without Chemotherapy. J Clin Oncol, 2014 Apr 7, Epub ahead of print

5.         X Zhang, W Ma, J Cui, H Yao, H Zhou, Y Ge, L Xiao, X Hu, BH Liu, J Yang, YY Li, S Chen, CJ Eaves, De-pei Wu*, Y Zhao*, Regulation of p21 by TWIST2 contributes to its tumor-suppressor function in human acute myeloid leukemia. Oncogene, 2015 Jun 4, 34(23):3000-10.

6.         Xiaojin Wu, Yao Yao, Xiaojing Bao, Huifeng Zhou, Xiaowen Tang, Yue Han, Xiao Ma, Yuejun Liu, Jia Chen, Haixia Zhou, Song Jing, Bing Gu, Yang Xu, Aining Sun, Jun He, Depei Wu.KIR2DS4 and Its Variant KIR1D Are Associated with Acute Graft-versus-Host Disease, Cytomegalovirus, and Overall Survival after Sibling-Related HLA-Matched Transplantation in Patients with Donors with KIR Gene Haplotype A. Biol Blood Marrow Transplant. 2016 Feb;22(2):220-5.

7.         Hong Tian, Guang-Hua Chen, Yang Xu, Xiao Ma, Feng Chen, Zhen Yang, ZhengMing Jin, HuiYing Qiu, AiNing Sun, DePei Wu*. Impact of pre-transplant disease burden on the outcome of allogeneic hematopoietic stem cell transplant in refractory and relapsed acute myeloid leukemia: a single-center study. Leuk Lymphoma. 2015 May;56(5):1353-61.

8.         Tao T, Ma X, Yang J, Zou JY, Ji SM, Tan YS, Gong W, Du F, Xu J, Ye CM, Tang XW, Wu DP*, Xue SL*. Humanized anti-CD25 monoclonal antibody treatment of steroid-refractory acute graft-versus-host disease: a Chinese single-center experience in a group of 64 patients. Blood Cancer. 2015 Apr 17;5:e308.

9.         Yang Xu, Yanjun Sun, Hongjie Shen, Lin Ding, Zhen Yang, Huiying Qiu1, Aining Sun, Suning Chen*, Depei Wu*.Allogeneic hematopoietic stem cell transplantation could improve survival of cytogenetically normal adult acute myeloid leukemia patients with DNMT3A mutations. Am J Hematol. 2015 Nov;90(11):992-7.

10.     Qi Qu, Limin Liu, Yanming Zhang, Xiaoli Li, Depei Wu*. Increasing aclarubicin dosage of the conventional CAG (low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor) regimen is more efficacious as a salvage therapy than CAG for relapsed/refractory acute myeloid leukemia. Leuk Res. 2015 Dec;39(12):1353-9.

11.     Depei Wu, Xin Du, Jie Jin, Zhijian Xiao, Zhixiang Shen, et al. Decitabine for treatment of myelodysplastic syndromes in Chinese patients: an open-label, phase-3b study. Adv Ther. 2015 Nov;32(11):1140-59.

12.     Limin Liu, Qi Qu, Wenjing Jiao, Yanming Zhang, Xiaoli Li, Chao Ding, Depei Wu*. Increasing aclarubicin dose in low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) is efficacious as salvage chemotherapy for relapsed/refractory mixed-phenotype acute leukemia. Leuk Res. 2015 Aug;39(8):805-11.

13.     Limin Liu#, Wenjing Jiao#, Yanming Zhangb, Qi Qua, Xiaoli Lia, Depei Wu*. Efficacy of low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) compared to Hyper-CVAD regimen as salvage chemotherapy in relapsed/refractory Philadelphia chromosome-negative acute lymphoblastic leukemia. Leuk Res. 2015 Mar;39(3):323-8.

14.     Xiaopeng Tian, Yang Xu, Jia Yin, Hong Tian, Suning Chen, Depei Wu*, Aining Sun*. TET2 gene mutation is unfavorable prognostic factor in cytogenetically normal acute myeloid leukemia patients with NPM1(+) and FLT3-ITD- mutations. Int J Hematol. 2014 Jul;100(1):96-104.

15.     Limin Liu, Yanming Zhang, Zhengming Jin, Xingxia Zhang, Guangsheng Zhao, Yejun Si, Guoqiang Lin, Aidi Ma, Yingxin Sun, Li Wang, Depei Wu*. Increasing the dose of aclarubicin in low-dose cytarabine and aclarubicin in combination with granulocyte colony-stimulating factor (CAG regimen) can safely and effectively treat relapsed or refractory acute myeloid leukemia. Int J Hematol.2014;99(5):603-8.

16.     Jia Chen, R-X Wang, Feng Chen, Aining Sun, Huiying Qiu, Zhengming Jin, Xiaowen Tang, Yue Han, Zhengzheng Fu, Guangsheng He, Miao Miao, Xiao Ma and Depei Wu*. Combination of a haploidentical SCT with an unrelated cord blood unit: a single-arm prospective study. Bone Marrow Transplant. 2014 Feb;49(2):206-11.

17.     Zhou H, Bao X, Wu X, Tang X, Wang M, Wu D*, He J*. Donor selection for Killer Immunoglobulin-like Receptors B haplotype of the centromeric motifs can improve the Outcome after HLA-identical sibling hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2014 Jan;20(1):98-105

18.     Ling Ge, Fan Ye, Xinliang Mao, Jia Chen, Aining Sun, Xiaming Zhu, Huiying Qiu, Zhengming Jin, Miao Miao, Chengcheng Fu, Xiao Ma, Feng Chen, Shengli Xue, Changgeng Ruan, Depei Wu*, Xiaowen Tang*. Extramedullary relapse of acute leukemia after allogeneic hematopoietic sem cell transplantation: different characteristics between acute myelogenous leukemia and acute lymphoblastic leukemia. Biol Blood Marrow Transplant. 2014 Jul;20(7):1040-7.

19.     Qian Zhu, Hong Wang, Jia Ruan, Lingchuan Guo, Shixiang Zhao, Wenjuan Zhang, Qian Wang, Zhengming Jin, Xiaochen Chen, Aining Sun, Depei Wu*, Yue Han*. Analysis of prognostic factors for survival in 75 Chinese patients with peripheral T-cell lymphoma. Leuk Lymphoma. 2014 Apr;55(4):959-61.

 

Others:

Director of Hematology department of the First Affiliated hospital of Soochow University;

Vice director of Jiangsu Institute of Hematology

Vice-dean of Medical Research College of Soochow University;

Vice-president of Hematology Branch of Chinese Medical Association (CMA);

Vice-president of Hematology Physicians Branch of Chinese Medical Doctor Association (CMDA).